Methods for diagnosing and controlling complications in cardiopulmonary transplants

Objectives:

This line of research includes clinical and experimental model studies on the prevention and early diagnosis of complications related to primary graft dysfunction and rejection in heart and lung transplants.

Faculty:

Fabiana Goulart Marcondes Braga
Marcelo Biscegli Jatene
Paulo Manuel Pêgo Fernandes
Rogério Pazetti

Active Projects:

  • Evaluation of experimental models of lung donors for transplantation
  • Primary graft dysfunction in adult patients undergoing heart transplantation: prospective analysis of prevalence, risk factors, and biomarkers
  • Effect of placlitaxel in combination with lipid nanoemulsions on the peribronchial and perivascular inflammatory process after unilateral left lung transplantation in rats
  • Effects of tacrolimus on mucociliary clearance in rats
  • Comparative study between sternal closure with sternal fixation plate versus wire steel in patients undergoing transesternal anterior bithoracotomy (clamshell incision) for bilateral lung transplantation
  • Lung transplantation in animal donor model, whether or not subjected to partial liquid ventilation with perfluorooctilbromide